Songlin Chen, Ph.D, Professor, Doctoral Supervisor.

Address: Yellow Sea Fisheries Research Institute, CAFS, 106 Nanjing Road, 266071, Qingdao, Shandong, P. R. China

Telephone:+86-532-85844606

Email:[email protected]

Personal Profiles:

Chief Scientist on Aquaculture Biotechnology, Chinese Academy of Fishery Sciences (CAFS);

Professor of Yellow Sea Fisheries Research Institute (YSFRI), CAFS;

Director ofLab for Aquaculture Genomics and Cell Engineering, YSFRI;

Director in Aquaculture Biotechnology Branch, China Society of Fisheries;

Taishan Scholar in Aquatic Germplasm Resources and Biotechnology, 2007-now;

Doctoral Supervisor in Ocean University of China and Shanghai Ocean University; Adjunct professor of Hua-Zhong Agriculture University and Jimei University.

Member of Editorial Committee of《Marine Biotechnology》.

Deputy director of Editorial Committee of《Journal of Fisheries of China》.

Research Interests:

The major interests are involved in genetic resource Exploration and molecular breeding in marine fishes, including

1. Marine fish genomics and exploitation of genomic resources;

2. Sex determination and sex control, and breeding by cell engineering；

3. Genome selection for high-yield and disease-resistant varieties;

4. Cell culture, Cryopreservation of sperm and embryos, Sperm Bank establishment.

Publications, books and patents

Over 300 papers were published，of which more than 120 were indexed by SCI including many top journals, such as Nature Genetics, Genome Research et al, as the chief editor in three books and the major contributor in 28 patents.

Projects and Major Honors

Over 20 projects at national, provincial and ministerial-level were conducted, includingNaturalScienceFoundationofChina(key research project), 863, 973, Special Fund for Agro-scientific Research in the Public Interest et al..2006 obtained Second class prize of National Technological Invention Awards(The First contributor), 2010 obtained Second class prize of National Science-Technology Progress Prize (The Second contributor), two time of first-class and five times of second-class scientific and technical award at provincial and ministerial-level (The First contributor). Moreover, over 10 other rewards were obtained including 3rd China Young Science and Technology Award (1992), Middle and Young Outstanding Scientist Award granted by Ministry of Agriculture (1997), Talent Project of Hundred, Thousand and Ten-thousand awarded by Ministry of Personnel (1997), Qingdao Outstanding Professional and Technological talent awards (2004); Shandong Province Middle and Young Outstanding Scientist Award (2005) and special allowance of the State Council.

Selected Publications

1. Chen Songlin*, Zhang Guojie, Shao Changwei, Huang Quanfei, LiuGeng, Zhang Pei, et al. 2014 Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to benthic life. Nature Genetics, 2014，46（3）：253-260. (* Corresponding author, the same below）

2. Shao Changwei, Li Qiye, Chen Songlin*, et al. 2014 Epigenetic modification and inheritance in sexual reversal of fishes. Genome Research,2014, doi:10.1101/gr.162172.113

3. Zhang JJ, Shao CW, Zhang LY, Liu K, Gao FT, Dong ZD, Xu P, Chen SL* 2014 A first generation BAC-based physical map of the half-smooth tongue sole (Cynoglossus semilaevis) genome. BMC Genomics, 15: 215 doi: 10.1186/1471-2164-15-21

4. Hu Qiaomu，Liang Zhuo，Li Yangzhen, Zhang Jing, Liu Shanshan, Gao Fengtao，Yang Jingfeng，Du Min, Chen Song-Lin * 2014 Sex ratio and growth characteristics of cultured stocks and families in half-smooth tongue sole (Cynoglossus semilaevis). Aquaculture International, DOI 10.1007/s10499-014-9757-7.

5. Lei Wang, Caixia Fan, Yang Liu, Yingping Zhang, Shoutang Liu, Deqiang Sun, Han Deng, Ying Xu, Mingshu Xie, Wenlong Li, Yongsheng Tian, Songlin Chen^*2014 A genome scan for quantitative trait loci associated with Vibrio anguillarum infection resistance in Japanese flounder (Paralichthys olivaceus) by bulked segregant analysis。Mar Biotech. DOI 10.1007/s10126-014-9569-9.

6. Sha Z, Gong G, Wang S, Lu Y , Wang L, Wang Q, Chen SL* 2014Identification and characterization of Cynoglossus semilaevis microRNA response to Vibrio anguillarum infection through high-throughput sequ encing. Dev Comp Immunol 44 (2014) 59–69

7. Na Wang, Xian-Li Wang, Chang-Geng Yang, Yu-Xi Zhang, TianZhi Wang, Song-Lin Chen* 2014 Molecular cloning and multifunctional characterization of GRIM-19 (Gene associated with Retinoid-Interferon-induced Mortality 19) homologue from turbot (Scophthalmus maximus). Dev Comp Immunol, 43(1):96-105.

8. Ting-ting Wang, Na Wang, Xiao-lin Liao，Liang Meng, Yang Liu Song-Lin Chen* 2013 Cloning, molecular characterization and expression analysis of heat shock cognate 70 (Hsc70) cDNA from turbot (Scophthalmus maximus). Fish Physiol Biochem. 39（6）：1377-1386.

9. Na Wang, Xian-Li Wang^a, Chang-Geng Yang, Song-Lin Chen* 2013 Molecular cloning, subcelluar location and expression profile of signal transducer and activator of transcription 2 (STAT2) from turbot, Scophthalmus maximus. Fish Shell Immunology, 35:1200-1208.

10. Shao Changwei, Liu Geng, Liu Shanshan, Liu Changlin, and Chen Songlin* 2013 Characterization of the cyp19a1a gene from a BAC sequence in half-smooth tongue sole and analysis of its conservation among teleosts。Acta Ocean Sin. 32( 8): 35-43.

11. Chang-Geng Yang, Xian-Li Wang, Bo Zhang, Bing Sun, Shan-Shan Liu and Song-Lin Chen* 2013 Protein interaction with PoAkirin1 by yeast two-hybrid assays and the roles in response to the immunological stimulants of these genes in Japanese flounder (Paralichthys olivaceus). BMC Mol Biol, 14:10. DOI: 10.1186/1471-2199-14-10

12. Hu QM, Chen SL 2013 Cloning, genomic structure and expression analysis of Ubc9 in development in half smooth tongues sole Cynoglossus semilaevis". Comp Biochem Physiol B. 165：181-188。.

13. Tian YS, Qi WS, Jiang J, Wang N, Wang D, Zhai JM, Chen C, Chen SL 2013 Sperm cryopreservation of sex-reversed seven-band grouper,Epinephelus septemfasciatu. Animal Repro. Science, 137:230-236.

14. Xiaolin Liao, Lei Cheng, Peng Xu, Guoqing Lu, Michael Wachholtz4, Xiaowen Sun, Songlin Chen* 2013 Transcriptome analysis of crucian carp (Carassius auratus), an important aquaculture and hypoxia-tolerant species. PLoS ONE 8(4): e62308. doi:10.1371/journal.pone.0062308

15. Chang-Geng Yang, Shan-shan Liu, Bing Sun, Xian-Li Wang, Na Wang，Song-Lin Chen* 2013 Iron-metabolic function and potential antibacterial role of Hepcidin and its correlated genes (Ferroportin 1 and Transferrin Receptor) in Turbot (Scophthalmus maximus). Fish Shell Immunol., 34:744-755。

16. Wentao SONG, Guidong MIAO, Yongwei ZHAO, Yuze NIU, Renyi PANG, Xiaolin LIAO, Changwei SHAO, Songlin CHEN* 2013 Construction of a microsatellite-based genetic linkage map of half-smooth tongue sole (Cynoglossus semilaevis). Current Zool., 59（1）：99-108.

17. Wen-Tao Song, Yang-Zhen Li，Yong-Wei Zhao , Yang Liu1, Yu-Ze Niu1, Ren-Yi Pang1, Gui-Dong Miao1, Xiao-Lin Liao, Chang-Wei Shao, Feng-Tao Gao, Song-Lin Chen* 2012 Construction of a high-density microsatellite genetic linkage map and mapping of sexual and growth-related traits in half-smooth tongue sole (Cynoglossus semilaevis). PLOS One，2012，7(12):e52097. Doi: 10.1371/journal.pone.0052097

18. Song W, Pang R, Niu Y, Gao F, Zhao Y, Zhang J, Sun J, Shao C, Liao X, Wang L, Tian Y, Chen S * 2012 Construction of High-Density Genetic Linkage Maps and Mapping of Growth-Related Quantitative Trail Loci in the Japanese Flounder (Paralichthys olivaceus). PLoS ONE 7(11): e50404. doi:10.1371/journal.pone.0050404。

19. Yuan Zheng, Na Wang, Ming-shu Xie, Zhen-xia Sha, Song-lin Chen* 2012 Establishment and characterization of a new fish cell line from head kidney of half smooth tongue sole (Cynoglossus semilaevis ). Fish Physiology Biochem，38:1635–1643.

20. Xian-Li Wang, Yu-Xi Zhang, Liang Meng, Song-Lin Chen* 2012 Cloning, characterization and expression analysis of a cold shock domain family member YB-1 in turbot Scophthalmus maximus。Fish Shell Immunol., 33(5): 1215-1221

21. Min Du，Song-lin Chen*, Jing-feng Yang 2012 MHC polymorphism and disease resistance to Edwardsiella tarda in 6 families in turbot (Scophthalmus maximus). Chin Sci Bull, 57 (25):3262-3269 .

22. Zhen-Xia Sha, Qi-Long Wang, Yang Liu, Song-Lin Chen* 2012 Identification and expression analysis of goose type lysozyme in half smooth tongue sole (Cynoglossus semilaevis). Fish Shell Immunol, 32:914-921.

23. Chen Song-Lin, Ji Xiang-Shan, Shao Chang-Wei, Li Wen-Long, Yang Jing-Feng, Liang Zuo, Liao Xiao-Lin, Xu Gen-Bo, Xu Ying, Song Wen-Tao 2012 Induction of mito-gynogenetic diploids and identification of WW super-female using sex-specific SSR markers in half-smooth tongue sole (Cynoglossus semilaevis)。Mar Biotechnol, 14(1) :120-128...

24. Ma Hongyu, Chen Songlin. 2011 Development of polymorphic microsatellite markers in barfin flounder (Verasper moseri) and spotted halibut (Verasper variegatus) by the cross-species amplification, Mol Biol Rep,38:4545-4551.

25. Ma Hongyu, Chen Songlin Yang Jingfeng, Chen Siqing, Liu Hanwen. 2011 Genetic linkage maps of barfin flounder (Verasper moseri) and spotted halibut (Verasper variegatus) based on AFLP and microsatellite markers. Mol Biol Report, 38:4749-4764.

26. Tian-jun Xu, Song-lin Chen 2011 Molecular cloning, genomic structure and expression analysis of major histocompatibility complex class Iα gene of half-smooth tongue sole (Cynoglossus semilaevis). Fish Physiol Biochem; Mar;37(1):85-90

27. Yong-sheng Tian, Tian-jun Xu , Liang You, Song-lin Chen 2011 Estimates of genetic and phenotypic parameters for weight and length in Paralichthys olivaceus (Temminck et Schlegel). Acta Ocean Sin.,30(6):58-64 .

28. Min Du, Song-lin Chen, Yan-hong Liu, Yang Liu, Jing-feng Yang 2011 MHC polymorphism and disease resistance to vibrio anguillarum in 8 families of half-smooth tongue sole (Cynoglossus semilaevis). BMC Genet. 12 :78

29. Ma HY, Chen SL, Ma LB, Hu QM 2011 A first set of gene-derived polymorphic microsatellite markers in half-smooth tongue sole (Cynoglossus semilaevis ). Environ Biol Fish, 91:501-504.

30. Min Du Song-lin Chen You Liang, Lei Wang Feng-tao Gao, Yang Liu, Xiaolin Liao 2011 Polymorphism and balancing selection of MHC class II DAB gene in 7 selective flounder (Paralichthys olivaceus) families. Evidence-Based Complementary and Alternative Medicine, Volume 2011, Article ID 613629, 10 pages. .

31. Sha ZX, Luo XH, Liao XL, Wang QL, Wang SL, Chen SL. 2011 Development and characterization of 60 novel EST-SSR markers in half-smooth tongue sole (Cynoglossus semilaevis). J Fish Biol, 78(1):322-31.

32. X. L. Dong, S. L. Chen and X.S. Ji 2011 Molecular cloning, characterization and expression analysis of Sox9 and Foxl2 genes in half-smooth tongue sole (Cynoglossus semilaevis). Acta Ocean Sin, 30 (1):68-77

33. Gui-dong Miao, Han-Wen Liu, Hong-yu Ma Song-lin Chen Ting-jun Fan, 2011 Isolation and characterization of 54 ploymorphic microsatellite loci for half-smooth tongue sole ,Cynoglossus semilaevis. J the World Aqua Society, 42(3):462-467.

34. Bo Zhang, Xianli Wang, Zhenxia Sha, Changgeng Yang, Shanshan Liu, Na Wang, Song-Lin Chen 2011 Establishment and Characterization of a Testicular Cell Line from the Half-Smooth Tongue Sole, Cynoglossus semilaevis. Int J Biol Sci., 7:452-459.

35. Yang CG, Wang XL, Wang L, Zhang B, Chen SL , 2011 A new Akirin1 gene in turbot (Scophthalmus maximus): Molecular cloning, characterization and expression analysis in response to bacterial and viral immunological challenge. Fish Shell Immunol, 30:1031-1041 .

36. Ji XS, Liu HW, Chen SL, Jiang YL, Tian YS 2011 Growth differences and dimorphic expression of growth hormone (GH) in female and male Cynoglossus semilaevis after male sexual maturation. Mar Genomics. 4:9-16.

37. Na Wang, Chang-Geng Yang, Zhong-Zhi Sun, Xian-Li Wang, Song-Lin Chen 2011 Signal transducer and activator of transcription 3 (STAT3) homologue in turbot (Scophthalmus maximus): Molecular characterization and expression analysis. Fish Shell Immunol.., 30:255-262.

38. Xiang-Shan Ji, Song-Lin Chen, Yun-Liang Jiang, Tian-Jun Xu, Jing-Feng Yang, Yong-Sheng Tian 2011 Growth differences and diffenential expression analysis of pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing normone(GHRH) between the sexes in half-smooth tongue sole Cynoglossus semilaevis. Gen Comp Endocri, 170:99-109.

39. N Wang, X-L Wang, Z-X Sha, Y-S Tian, S-L Chen 2011 Establishment, characterization and virus susceptibility of a kidney-derived cell line from southern flounder, Paralichthys lethostigma. Jordan& Gilbert. J Fish Dis, 34:81-85.

40. Tian-jun Xu, Yue-na Sun, Song-Lin Chen 2010 Allelic variation, balancing selection and positive selected sites detected from MHC class Ia gene of olive flounder. Genetica, 138:1251-1259.

41. N Wang, X-L Wang, Z-X Sha, Y-S Tian, S-L Chen 2010 Development and characterization of a new marine fish cell line from turbot (Scophthalmus maximus). Fish Physio Biochem, 36(4):1227-1230

42. Wang XL, Wang N, Sha ZX, Chen SL 2010 Establishment, characterization of a new cell line from heart of half-smooth tongue sole (Cynoglossus semilaevis). Fish Physio Biochem, 36(4):1181-1184.

43. Xiang-Shan Ji, Song-Lin Chen, Jing-Feng Yang, Hong-Yu Ma, Yun-Liang Jiang 2010 Artificial gynogenesis and assessment of homozygosity in meiotic gynogens of spotted halibut (Verasper variegatus). Aquaculture Internal. 18(6):1151-1161.

44. Shao CW, Chen SL, Scheuring CF., Xu JY, Dong XL, Zhang HB 2010 Construction and Characterization of Two Bacterial Artificial Chromosome Libraries of Half-smooth Tongue Sole, Cynoglossus semilaevis, and Isolation of Clones Hybridizing with Female-specific Markers and Sex-related Genes. Mar Biotech, 12:558-568.

45. Tian-jun Xu, Song-lin Chen, Yu-xi Zhang 2010 MHC class IIa gene polymorphism and its association with resistance/susceptibility to Vivrio anguillarum in Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol, 34:1042-1050.

46. Xu TJ, Chen SL 2010 Induction of All-triploid Japanese Flounder (Paralichthys olivaceus) by Cold Shock. ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH, 62 (1): 43-49.

47. Ji XS, Tian YS, Yang JF, Wu PF, Jiang YL, Chen SL 2010 Artificial gynogenesis in Cynoglossus semilaevis with homologous sperm and its verification using microsattlite markers. Aquaculture Research, 41 (6): 913-920 .

48. Gen-Bo Xu, Song-Lin Chen and Yong-Sheng Tian 2010 New polymorphic microsatellite makers for bluefin leatherjacket (Navodon septentrionalis Gunther,1877).Conser Genet, 11(3):1111-1113. (IF 1.85)

49. S.L. Chen, Y. Liu, X.L. Dong, L. Meng 2010 Cloning, characterization，and expression analysis of a CC chemokine gene from turbot (Scophthalmus maximus). Fish Physiol Biochem, 36：147-155. (IF 1.23).

50. SHA Zhenxia, REN Guocheng, WANG Xianli, WANG Na, CHEN Songlin 2010 Development and characterization of a cell line from the embryos of half smooth tongue sole (Cynoglossus semilaevis). Acta Oceanol Sin, 29(2):81-87.

51. Zhenxia Sha, Shaolin Wang, Zhimeng Zhuang, Qingyin Wang, Qilong Wang, Ping Li, Hao Ding, Na Wang, Zhangjiang Liu, Songlin Chen 2010 Generation and analysis of 10,000 ESTs from the half smooth tongue sole, Cynoglossus semilaevis and identification of microsatellite and SNP markers. Journal of Fish Biology, 76:1190-1204.

52. Ma H, Chen S,，Yang J., Ji X., Chen S., Tian Y., Bi J 2010 Isolation of Sex-specific AFLP markers in spotted halibut (Verasper variegatus). Environ Biol Fish, 88:9-14 .

53. Tian-jun Xu, Zhen-xia Sha, Song-lin Chen 2010 Unexpected variations of β2-microglobulin gene in the half-smooth tongue sole. Fish Shell Immunol. 28:212-215.

54. Shao CW, Wu PF, Wang XL, Tian YS, Chen SL 2010 Comparison of Chromosome Preparation methods for the Different Developmental Stages of the Half-smooth Tongue Sole, Cynoglossus Semilaevis. Micron, 41:47-50.

55. Shi-Chao XING, Gen-Bo XU, Guan-Pin Yang, Shan-Shan LIU, Xiao-Lin LIAO Yong-sheng Tian? and Song-Lin CHEN* 2009 Isolation and characterization of 30 novel polymorphic microsatellite loci from Japanese halfbeak（日本箴）, Hyporhamphus sajori (Temminck et Schlegel, 1846). Conser Genet, 10:1927-1930.

56. Zhen-Xia SHA, Shi-Chao XING, Chang-Wei SHAO, Yong-Sheng TIAN, Xiao-Lin LIAO, Song-Lin CHEN* 2009 Isolation and characterization of 12 polymorphic microsatellite markers from ladyfish ( Elops saurus Linnaeus ). Conser Genet,，10:1799-1801.

57. Xiaolin Liao, Hong-Yu Ma, Gen-Bo Xu, Chang-Wei Shao, Yong-Sheng Tian, Xiang-Shan Ji, Jing-Feng Yang, Song-Lin CHEN* 2009 Construction of a genetic linkage map and mapping of a female-specific DNA marker in half-smooth tongue sole (Cynoglossus semilaevis). Mar Biotech, 11(6):699-709.

58. Hongyu Ma, Song-Lin CHEN* 2009 Isolation and characterization of 31 polymorphic microsatellite markers in barfin flounder (Verasper moseri) and the cross-species amplification in spotted halibut (Verasper variegatus). Conserv Genet, 10:1591-1595.

59. Jing-Feng YANG, Li-Li ZHAO, Chang-Wei SHAO, Xiang-Shan JI, Xiao-Lin LIAO, Song-Lin CHEN* 2009 Isolation and characterization of polymorphic microsatellite loci from black snapper Sebastodes fuscescens (Houttuyn). Conserv Genet, 10:1541-1543.

60. Song-Lin CHEN*, Shi-Chao XING, Gen-Bo XU, Xiaolin LIAO, Jing-Feng YANG 2009 Isolation and characterization of 10 polymorphic microsatellite loci from small yellow croaker (Pseudosciaena polyactis). Conserv Genet 10:1469-1471.

61. Song-Lin CHEN*, Gui-Dong Miao, Chang-Wei SHAO, Yong-Sheng TIAN，Xiaolin LIAO 2009 Isolation and characterization of polymorphic microsatellite loci from fat greenling (Hexagrammos otakii). Conserv Genet 10:1429-1431.

62. X-S Ji, Song-Lin CHEN*, X-L Liao, J-F Yang, T-J Xu, H-Y Ma, Y-S Tian, Y-L Jiang, P-F Wu 2009 Microsatellite-centromere mapping in Cynoglossus semilaevis using gynogenetic diploid families produced by the use of homologous and non-homologous sperm. J Fish Biol, 75:422-434.

63. H. Y. Ma, J. Z. Bi, C. W. Shao, Y. Chen, G. D. Miao, Song-Lin CHEN* 2009 Development of 40 microsatellite markers in spotted halibut (Verasper variegatus) and the cross-species amplification in barfin flounder (Verasper moseri). Anim Genet, 40:576-578.

64. Tian-jun Xu Song-Lin CHEN* Xiang-shan Ji，Zhen-xia Sha 2009 Molecular cloning, genomic structure, polymorphism and expression analysis of major histocompatibility complex class IIA and IIB genes of half-smooth tongue sole (Cynoglossus semilaevis). Fish Shell Imunol., 27：192-201.

65. Gen-Bo Xu, Yong-Sheng Tian, Xiao-Lin Liao and Song-Lin CHEN*n 2009 Isolation and charaterization of polymorphic microsatellite loci from bluefin leatherjacket (Navodon septentrionalis Gunther, 1877). Conserv Genet, 10:1181-1184

66. Shi-Chao Xing, Gen-Bo XU, Xiao-Lin LIAO，Guan-Pin YANG & Song-Lin CHEN* 2009 Twelve polymorphic microsatellite loci from a dinucleotide-enriched genomic library of Japanese spanish mackerel (Scomberomorus niphonius). Conserv Genet, 10:1167-1169.

67. Jin-Zhen Bi, Chang-Wei Shao, Gui-Dong Miao, Hong-Yu Ma, Song-Lin CHEN* 2009 Isolation and characterization of 12 microsatellite loci from cutlassfish (Trichiurus haumela). Conserv Genet, 10:1171-1173.

68. Song-Lin CHEN*, Lili ZHAO, Chang-Wei SHAO, Xiaolin LIAO, Yong-Sheng TIAN 2009 Isolation and characterization of polymorphic microsatellite loci from black sea bass (Centropristis striata) and cross-species amplification. Conserv Genet, 10:1101-1103.

69. Yong-Sheng Tian, Gui-Dong Miao, Chang-Wei Shao, Xiao-Lin Liao, Song-Lin CHEN* 2009 Isolation and characterization of polymorphic microsatellite loci from a repeat-enriched genomic library of stone flounder (Kareius bicoloratus) and cross-species amplification. Conserv Genet, 10:1041-1043.

70. Genbo Xu, Changwei Shao, Xiaolin Liao, Yongsheng Tian, Song-Lin CHEN* 2009 Isolation and charaterization of 12 dinucleotide microsatellite loci from Belenger’s jewfish (Johnius belengerii ). Conserv Genet, 10:1009-1011

71. J-Y Xu, Song-Lin CHEN*, H Ding 2009 Specific MHC class II B Allele Associated with Resistance to Edwardsiella tarda in Turbot (Psetta maxima). J Fish Disease, 32:637-640.

72. Xiang-Shan Ji, Song-Lin CHEN*, Hong-Yu Ma, Tian-Jun Xu, Xiao-Lin Liao,Yun-Liang Jiang 2009 Isolation and characterization of 19 EST-linked ploymorphic microsatellite loci for olive flounder (Paralichthys olivaceus). Aquaculture Research, 40:980-983.

73. Shichao Xing, Changwei Shao, Xiaolin Liao, Yongsheng Tian, Song-Lin CHEN* 2009 Isolation and characterization of polymorphic microsatellite loci from a dinucleotide-enriched genomic library of Spotted maigre (Nibea albiflora). Conservation Genetics, 10:789-791.

74. Lili Zhao, Changwei Shao, Xiaolin Liao, Hongyu Ma, Xuechun Zhu, Song-Lin CHEN* 2009 Twelve novel polymorphic microsatellite loci for the Yellow grouper(Epinephelus awoara) and cross-species amplifications. Conservation Genetics, 10:743-745.

75. Changwei SHAO, Genbo Xu, Lei Wang, Xiaolin LIAO X, Yongsheng TIAN, Song-Lin CHEN*. 2009 New polymorphic microsatellite markers for the summer flounder, Paralichthys dentatus. Conservation Genetics, 10:717-719. .

76. Gui-Dong Miao, Chang-Wei Shao, Xiao-Lin Liao, Hong-Yu Ma, Yong-Sheng Tian, Song-Lin CHEN* 2009 Developement of polymorphic microsatellite markers from barfin flounder (Verasper moseri) and their cross-species amplification. Conservation Genetics, 10:701-703.

77. Genbo Xu, Changwei Shao, Xiaolin Liao Yongsheng Tian and Song-Lin CHEN* 2009 Isolation and charaterization of polymorphic microsatellite loci from so-iuy mullet (Mugil soiuy Basilewsky 1855. Conservation Genetics, 10:653-655.

78. ZHAO Lili, SHAO Changwei, LIAO Xiaolin, Song-Lin CHEN* 2009 Isolation and characterization of polymorphic microsatellite loci from a dinucleotide-enriched genomic library of seven-band grouper (Epinephelus septemfasciatus) and cross-species amplification. Conservation Genetics, 10:627-629.

79. Guidong MIAO, Changwei SHAO, Hongyu MA, Xiaolin LIAO, Song-Lin CHEN* 2009 Isolation and characterization of polymorphic microsatellite loci from a dinucleotide-enriched genomic library of starry flounder (Platichthys stellatus) and cross-species amplification. Conservation Genetics, 10:631-633.

80. Chaowei Shao, Song-Lin CHEN*, Genbo Xu, Xiaolin Liao, Yongsheng Tian, 2009 Eighteen novel microsatellite markers for the Chinese sea perch, Lateolabrax maculatus. Conservation Genetics, 10:623-625.

81. Hao Ding, Changwei Shao, Xiaolin Liao, Genbo Xu, Xiangshan Ji, Song-Lin CHEN* 2009 Ten polymorphic microsatellite loci for the Atlantic halibut (Hippoglossus hippoglossus) and cross-species application in related species. Conservation Genetics, 10:611-614.

82. T. XU, C. SHAO, X. LIAO, X JI, Song-Lin CHEN* 2009 Isolation and characterization of polymorphic microsatellite DNA markers in the rock bream (Oplegnathus fasciatus). Conservation Genetics, 10:527-529.

83. Hong-Yu Ma, Song-Lin CHEN*, Xionlin Liao, Jia chun Ge 2009 Isolation and characterization of polymorphic microsatellite loci from a dinucleotide-enriched genomic library of obscure puffer (Takifugu obscurus) and cross-species amplification. Conserv Genet, 10:955-957.

84. Deng SP, Song-Lin CHEN* 2009 cDNA cloning, tissues, embryos and larvae expression analysis of Sox10 in half-smooth tongue-sole, Cynoglossus semilaevis. Mar Genomics. 1:109-114.

85. CHEN Song-lin, TIAN Yong-sheng, YANG Jing-feng, SHAO Chang-wei, ZHAI Jie-ming, Zhuang Zhi-Meng, JI Xiang-shan, LIAO Xiao-lin, LIU Shou-tang, SU Peng-zhi, XU Jian-yong, SHA Zhen-xia WU Peng-fei Wang Na 2009 Artificial gynogenesis and sex determination in half-smooth tongue sole (Cynoglossus semilaevis). Mar Biotech. 11(2):243-251.

86. Jian-Yong Xu, Gen-Bo Xu, Song-Lin CHEN* 2009 A New Method for SNP discovery. BioTechnique. 46(3):115-121.

87. Si-Ping Deng, Song-Lin CHEN*, Jian-Yong Xu, Ben-Wei Liu 2009 Molecular cloning, characterization and expression analysis of gonadal P450 aromatase in the half-smooth tongue-sole, Cynoglossus semilaevis. Aquaculture, 287：211-218.

88. MA, Hongyu; Song-Lin CHEN*; LI, Jing; BI, Jinzhen; XU, Tianjun 2009 Cloning, characterization of two female-specific AFLP markers and development of PCR-based sex identification method for the half-smooth tongue sole Cynoglossus semilaevis. Current Zoology, 55(4):309-314。

89. MA Hongyu, YANG Jingfeng, SU Pengzhi, CHEN Song-Lin* 2009 Genetic analysis of gynogenetic and common population of Verasper moseri using SSR markers. Wuhan University Journal of Natural Sciences, 14:267-273.(EI收錄)

90. Yong-Sheng Tian, Song-Lin CHEN*, Xiang-Shan Ji, Jie-Ming Zhai, Li-Juan Sun, Chao Chen, Peng-Zhi Su 2008 Cryopreservation of spotted halibut (Verasper variegatus) sperm. Aquaculture, 284:268-271.

91. Song-Lin CHEN*, SHAO CW, Xu GB, LIAO X, Tian YS 2008 Development of 15 novel dinucleotide microsatellite markers in the Senegalese sole Solea senegalensis. Fisheries Science. 74:1357-1359.

92. Tian-jun Xu , Song-Lin CHEN* , Xiang-shan Ji, Yong-sheng Tian, Hong-yu Ma 2008 MHC polymorphism and disease resistance to Vibrio anguillarum in 12 selective Japanese flounder (Paralichthys olivaceus) familie. Fish Shell Immunol, 25:213-221.

93. SHAO C. W, LIAO X., Song-Lin CHEN* 2008 Isolation and characterization of microsatellite DNA loci from the Southern flounder, Paralichthys lethostigma. Mol Ecol Resou, 8:381-383.

94. Liu Yang, Song-Lin CHEN*, Meng L, Zhang YX 2007 Molecular identification and expression analysis of a CXCL10-like chemokine from turbot (Scophthalmus maximus). Aquaculture, 272, 199-207.

95. X. LIAO, C. W. SHAO, Y. S. TIAN, Song-Lin CHEN* 2007 Polymorphic dinucleotide microsatellites in tongue sole (Cynoglossus semilaevis Günther). Mol Ecol Note, 7（6）：1147-1149.

96. Chen S.L., Ma H.Y., Jiang Y, Liao X.L. Meng L 2007 Isolation and characterization of polymorphic microsatellite loci from an EST-library of turbot (Scophthalmus maximus) and cross-species amplification. Mol Ecol Note, 7(5):848-850

97. Yunguo Liu, Song-Lin CHEN*, Bafang Li 2007 Genetic differentiation among common and selected hatchery populations of Japanese flounder: Evidence from RAPD markers. Bioche. Syste. Ecol., 35：689-695

98. Ye HQ, Song-Lin CHEN* 2007 Molecular cloning and expression analysis of the Myf5 gene in sea perch (Lateolabrax japonicus). Comp Biochem Physio B,147:452-459.

99. Chen SL, Zhang YX, Xu JY et al., 2007 Molecular cloning and expression analysis of the natural resistance associated macrophage protein (Nramp) cDNA from turbot (Scophthalmus maximus). Comp Biochem Physio B, 147:29-37.

100. Liu Yang, Song-Lin CHEN*, Meng L, Zhang YX 2007 Cloning, characterization and expression analysis of a novel CXC chemokine from turbot (Scophthalmus maximus). Fish Shell Immunol, 23(4):711-720.

101. Chen Song-lin, Li Jing, Deng Si-ping, Tian Yong-Sheng, Wang Qing-yin, Zhuang Zhimeng, Sha Zhenxia, Xu Jianyong 2007 Isolation of female-specific AFLP markers and molecular identification of genetic sex in half-smooth tongue sole (Cynoglossus semilaevis). Mar Biotech, 9(2):273-280.

102. Ye HQ, Song-Lin CHEN*, Sha ZX, Liu Y 2007 Molecular cloning and expression analysis of the myostatin gene in sea perch (Lateolabrax japonicus). Mar Biotech, 9(2):262-272.

103. Chen Song-Lin, Sha Zhen-Xia, Ye Han-Qing, Liu Yang, Tian Yong-Sheng, Hong Yunhan, Tang Qi-Sheng 2007 Pluripotency and chimera competence of an embryonic stem cell line from sea perch (Lateolabrax japonicus), Mar Biotech, 9(1):82-91.

104. Chen Song-Lin, Li Wei, Meng Liang, Sha Zhen-Xia, Wang Zhi-Jian, Ren Guo-Cheng 2007 Molecular cloning and expression analysis of a hepcidin antimicrobial peptide gene from turbot (Scophthalmus maximus). Fish Shell Immunol，22:172-181.

105. Yu-Xi Zhang, Song-Lin CHEN* 2006 Molecular identification, polymorphism and expression analysis of major histocompatibility complex classⅡA and B genes of turbot (Scophthalmus maximus). Mar Biotech, 8(6):611-623.

106. Zhang YX, Song-Lin CHEN*, Liu YG, Sha zx, Liu Z 2006 Major histocompatibility complex classⅡB allele polymorphism and its association with resistance/susceptibility to Vibrio Anguillarum in Japanese flounder（Paralichthys olivaceus）. Mar Biotech，8(6):600-610.

107. Ying Chen, Yu-Xi Zhang, Tingjun Fan, Liang Meng, Guo-cheng Ren, Song-Lin CHEN* 2006 Molecular identification and expression analysis of the natural killer cell enhancing factor (NKEF) gene from turbot (Scophthalmus maximus). Aquaculture, 261:1186-1193.

108. Ye,Han-Qing Song-Lin CHEN*, Sha Zhen-Xia, Xu Mei-Yu 2006 Development and characterization of five cell lines from heart, liver, spleen and head kidney of sea perch (Lateolabrax japonicus). J Fish Biol., 69(Supplement A):115-126.

109. Liu Yunguo, Song-Lin CHEN*, Li Jing, Li Bafang 2006 Genetic diversity in three Japanese flounder (Paralichthys olivaceus) populations revealed by ISSR markers. Aquaculture, 255:565-572

110. Chen Song-Lin, Yu-Xi Zhang, Mei-Yu Xu, Xiang-Shan Ji, Guo-Cai Yu, Cheng-Fang Dong. 2006 Molecular polymorphism and expression analysis of MHC class IIβ gene from red sea bream (Chrysophrys major). Dev Comp Immunol., 30(4):407-418.

111. Chen Song-Lin *, Wang Zhi-Jian, Xu Mei-Yu, Gui Jian-Fang 2006 Molecular identification and expression analysis of natural resistance associated macrophage protein (Nramp) cDNA from Japanese flounder (Paralichthys olivaceus). Fish Shell Immunol., 20(3):365-373.

112. Chen SL, Ren GC, Sha ZX, Hong Y. 2005 Development and characterization of a continuous embryonic cell line from turbot (Scophthalmus maximus). Aquaculture, 249(1-4):63-68.

113. Liu YG, Song-Lin CHEN*, Li BF, Wang ZJ, Liu Z 2005 Analysis of genetic variation in selected stocks of hatchery flounder, Paralichthys olivaceus, using AFLP markers. Bioche. Syste. Ecol., 33:993-1005.

114. Chen SL, Xu MY, Ji XS, Yu GC, Liu Y. 2005 Cloning, characterization and expression analysis of hepcidin gene from red sea bream (Chrysophrys major). Antimicrob. Agents Chemo. 49(4):1608-1612.

115. Chen SL, Liu YG, Xu MY, Li J 2005 Isolation and characterization of polymorphic microsatellite loci from an EST-library of red sea bream (Chrysophrys major) and cross-species amplification. Molecular Ecology Note, 5:215-217.

116. Chen S.L., Tian Y.S. 2005. Cryopreservation of flounder embryos by vitrification. Theriogenology, 63(4):1207-1219.

117. Liu Y, Song-Lin CHEN*, Li B. 2005 Assessing the genetic structure of three Japanese flounder (paralichthys olivaceus) stocks by micrsatellite markers. Aquaculture, 243,103-111.

118. Ji XS, Song-Lin CHEN*, Yu GC, Tian YS, Sha ZX 2004 Cryopreservation of sperm from sea perch (Lateolabrax japonicus) and feasibility for production-scale fertilization. Aquaculture, 241:517-528.

119. Chen S.L., Xu M.Y., Hu S.N., Li L. 2004. Analysis of immune-relevant genes expressed in red sea bream spleen. Aquaculture, 240:115-130.

120. Chen S.L., Xu M.Y., Ji X.S., Yu G.C. 2004. Cloning and characterization of natural resistance associated macrophage protein (Nramp) cDNA from red sea bream (Pagrus major). Fish & Shellfish Immunology, 17(4):305-313.

121. Chen S.L., Ren G.C., Sha Z.X., Shi C.Y. 2004 Establishment of a continuous embryonic cell line from flounder (Paralichthys olivaceus) for virus isolation. Disease of Aquatic Organism, 60:241-246.

122. Chen S.L，Ji X.S., Yu G.C., Tian Y.S., Sha Z.X. 2004. Cryopreservation of spermatozoa from turbot (Scophthalmus maximus) and application to large scale fertilization. Aquaculture, 236:547-556。

123. Chen, S.L, Sha ZX, Ye HQ. 2003 Establishment of a pluripotent embryonic cell line from sea perch blastula embryo. Aquaculture, 218:141-151..

124. Chen S.L，Ye HQ, Sha ZX. 2003 Derivation of a pluripotent embryonic cell line from red sea bream blastulas. Journal of Fish Biology, 63:795-805.

125. Chen, S, Hong Y., Scherer SJ. Schartl M., 2001. Lack of ultraviolet-light inducibility of the medakafish (Oryzias latipes) tumor suppressor gene p53 . Gene，264:197-203

126.Chen, S.L.,Liu X.T.,Lu D.C.,Zhang, L.Z. 1993.Cryopreservation of Chinese carp spermatozoa. Aquaculture，lll:324～325。